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Induction — General

4 diseases · 0 criteria · structured C/P · Inves · Mng

C/P — Clinical Presentation
Inves — Investigations
Mng — Management
Special — Pathognomonic / disease-unique

Additions — Approach & OSCE

4 entries
1

Complicated Skin & Soft Tissue Infection (cSSTI)

C/P
  • Broad variety of pathogens, frequently polymicrobial
Inves
  • Clinical; culture to identify polymicrobial/resistant organisms
Mng
  • Simple abscess may respond to incision and drainage alone
  • Complex abscess with surrounding cellulitis requires adjuvant antibiotics
  • Suspected polymicrobial infection: cover enteric gram-negative and anaerobic pathogens
Special
  • Most common isolate: S. aureus (CA-MRSA increasingly common)
  • One of the four SSTI categories (with diabetic foot infection, non-necrotising cellulitis, NSTI)
2

Febrile Non-Haemolytic Transfusion Reaction (FNHTR)

C/P
  • Mild temperature rise (e.g., 36.8°C → 37.6°C) with otherwise stable observations
Mng
  • Monitor closely; consider paracetamol
  • Usually safe to proceed with caution if no other signs of a serious reaction
3

Transfusion-Associated Iron Overload

Special
  • Non-immune transfusion complication (chronic)
  • 200 mg elemental iron delivered per unit of packed red cells
  • A major cause of morbidity and mortality in patients with transfusion-dependent diseases (e.g., thalassaemia, sickle cell)
4

Dyshidrotic Eczema (Pompholyx)

C/P
  • Pruritic vesicular or bullous rash with a predilection for the hands and feet
  • Usually bilateral and may be symmetrical
  • Frequently develops or flares up in summer
  • Most common in teenagers and young adults
Inves
  • Clinical; histology if needed
Special
  • Vesicular eczema of hands/feet ('pompholyx' = ancient Greek for 'bubble')
  • Pathogenesis/triggers: abnormal sweating; nickel allergy; aggravated by stress; often related to other skin diseases (atopic/contact dermatitis, dermatophyte or bacterial infection)
  • Histology: acute spongiotic dermatitis with intraepidermal vesicles; thick stratum corneum indicates acral (hand/foot) skin